"Fortune found and replicated a flawed Super-Soldier serum that Mockingbird helped create. After ingesting it, he was de-aged and lost his memory for a short time.
In 2006, the newly de-aged Dominic Fortune joined forces with Silver Sable to stop the plans of traitors from within Silver Sable's own Wild Pack.[33] At that time Fortune worked as a P.I., but was also shown to be working with a government black ops group called the Vanguard.
After he regained his memory and aged overnight, he decided to join Mockingbird's organization, the World Counter-terrorism Agency to stay close to her, making sure the Super-Soldier serum's creator was there to help him if the side-effects got worse.
In 2015, he was revealed to have again aged (although still younger than his actual 100+ years) and living back on board the Mississippi Queen, left to him by the deceased Sabbath Raven. He enlisted the help of S.H.I.E.L.D. field director Phil Coulson to help him reacquire the ship after losing it while gambling with Hydra agent Tug Freehand."